Cell–cell adhesion-driven contact guidance and its effect on human mesenchymal stem cell differentiation
… of osteoblasts resulted in the disruption of apatite alignment and the … that link the actin
cytoskeleton inside the cell and ECM … -adhesive agents, such as PEG, for contact guidance. …
cytoskeleton inside the cell and ECM … -adhesive agents, such as PEG, for contact guidance. …
[HTML][HTML] Cellular and subcellular contact guidance on microfabricated substrates
C Leclech, C Villard - Frontiers in Bioengineering and Biotechnology, 2020 - frontiersin.org
… on stem cells and topography-induced stem cell differentiation, this … Disturbing the link
between FAs and actin stress fibers while … elements involved in contact guidance, such as actin. It …
between FAs and actin stress fibers while … elements involved in contact guidance, such as actin. It …
Hepatic differentiation of human embryonic stem cells by coupling substrate stiffness and microtopography
C Luo, D Lü, L Zheng, F Zhang, X Zhang, S Lü… - Biomaterials …, 2021 - pubs.rsc.org
… in accordance with the guidelines of the Institutional Animal and … a previously described
soft-contact lithography technique. Briefly, … We first used actin staining (white arrows) to illustrate …
soft-contact lithography technique. Briefly, … We first used actin staining (white arrows) to illustrate …
[HTML][HTML] Neuronal contact guidance and YAP signaling on ultra-small nanogratings
… -independent in human embryonic stem cells cultured on both … avoided nano-feature disruption
during NIL, ensuring the … We finally tested the effects of drugs acting on cell cytoskeleton…
during NIL, ensuring the … We finally tested the effects of drugs acting on cell cytoskeleton…
[HTML][HTML] Biomechanical, biophysical and biochemical modulators of cytoskeletal remodelling and emergent stem cell lineage commitment
… We explore how engineered materials target cytoskeletal remodeling and guide … contact
expansion that determines the anchoring strength of actin to E-cadherins in individual cells, …
expansion that determines the anchoring strength of actin to E-cadherins in individual cells, …
[HTML][HTML] Linking substrate and nucleus via actin cytoskeleton in pluripotency maintenance of mouse embryonic stem cells
… To address these questions, we investigated … impact on F-actin-catenin coefficient correlation
and F-actin-Nesprin connection disruption, we propose that the physical link between actin …
and F-actin-Nesprin connection disruption, we propose that the physical link between actin …
The relationship between substrate topography and stem cell differentiation in the musculoskeletal system
… can be explained by the contact guidance theory. … we fully understand the exact role played
by the actin cytoskeleton. … 3 weeks) of mouse embryonic stem cells for an extended duration […
by the actin cytoskeleton. … 3 weeks) of mouse embryonic stem cells for an extended duration […
[PDF][PDF] Cell position within human pluripotent stem cell colonies determines apical specialization via an actin cytoskeleton-based mechanism
… labeling in edge cells of embryonic stem cell colonies is due to … into single cells without any
cellular contact and then labeled … , disruption of actin dynamics with a ROCK inhibitor or actin …
cellular contact and then labeled … , disruption of actin dynamics with a ROCK inhibitor or actin …
[HTML][HTML] Nature-inspired topographies on hydroxyapatite surfaces regulate stem cells behaviour
… contact guidance phenomenon which leads to the formation of lamellipodia and filopodia
[40]. These two structures are both actin-… on a substrate tend to disrupt the formation of focal …
[40]. These two structures are both actin-… on a substrate tend to disrupt the formation of focal …
Manipulation of stem cells fates: the master and multifaceted roles of biophysical cues of biomaterials
X Wan, Z Liu, L Li - Advanced Functional Materials, 2021 - Wiley Online Library
… of stem cells, they are generally divided into embryonic stem … of focal adhesions with actin
filament remodeling, entrance of … the direction of parallel structures due to contact guidance. …
filament remodeling, entrance of … the direction of parallel structures due to contact guidance. …